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Jin Y, Lu L, Tu W, Luo T, Fu Z

It is worth mentioning that a recent study found that in tumors, the metabolite lactate affected the TME by regulating the lactylation of MOESIN in Tregs and enhancing TGF- signal transduction, thus promoting a new mechanism of tumorigenesis 266

When cMyc is overexpressed, it leads to coordinated changes in the expression of various gene families, which collectively enhance cellular growth and division