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GSH, the reduced form of glutathione, is primarily responsible for this antioxidant activity by directly scavenging free radicals and supporting cellular defense mechanisms

As the loss of POLRMT results in severe mitochondrial dysfunction in cardiac muscle 70 , a similar mitochondrial dysfunction should occur in beta-cells with the loss or dysfunction of POLRMT, resulting in insulin resistance and diabetes mellitus

(2012) investigated the cellular mechanisms by which NAC reduces the propensity for cocaine relapse in rodent models [12]

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Based on current investigations, ferroptosis triggered by P