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Some of the most common secondary causes include: Endometriosis This disorder occurs when tissue similar to the tissue that normally lines the inside of your uterus grows outside your uterus, often adhering to your bladder, ovaries, or even your bowels

[PubMed: 2871345] 45

130 COPD and the PI3K/Akt pathways The phosphatidylinositol 3 kinase (PI3K) pathway is a major pathway regulating cell growth, proliferation, metabolism, survival and angiogenesis

That pales in comparison to the 68.7% that has completed the primary series

So, folic acid or vitamin B12 deficiency can impair methylation processes, leading to disruptions in gene expression, neurotransmitter synthesis, and other cellular functions, potentially contributing to various health challenges