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Description

The thyroid is controlled through the hypothalamus-pituitary-thyroid axis, which is prone to circadian and seasonal changes

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However, it has also been suggested that CR-induced metabolic effects may be due to decreased protein intake in food-restricted animal models 4,5

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doi: 10.1158/0008-5472.CAN-11-2182 535 HutzenBFriedmanLSoboMLinLCenLDe AngelisSet al

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