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In addition, tumors are composed of heterogeneous components encompassing both malignant and non-malignant cell populations, and such intercellular heterogeneity renders the interpretation of heteroplasmy levels using conventional bulk sequencing approaches challenging [128]

Atkinson FS, Cohen M, Lau K, Brand-Miller JC (2023) Glycemic index and insulin index after a standard carbohydrate meal consumed with live kombucha: A randomised, placebo-controlled, crossover trial