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Under neuroinflammatory conditions, dysfunctional mitochondria release ROS and damage-associated molecular patterns (DAMPs) (53), activating microglia and astrocytes, and triggering the release of pro-inflammatory cytokines and chemokines (54), thereby exacerbating the damage

doi: 10.1097/MD.0000000000030760 352

The exception was XDIV, which did not have significant Quality weighting

Dugger TW, Sarkar S, Correa-Garhwal SM, Zhernenkov M, Zhang Y, Kolhatkar G, Mohan R , Cruz L, Lubio AD, Ruediger A, Hayashi CY, Uhrich KE, Kisailus DJ