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Current attempts such as the CobaSorb Test and tests employing a detectable non-radioactive form of B12 may prove to be reasonable alternatives for the original Schillings Test, and thereby help to solve the most important question: Will this patient need a lifelong treatment with pharmacological doses of B12

However, in a subanalysis of participants with low vitamin B 12 status at baseline (n= 101), the B-vitamin supplementation slowed the decline in bone mineral density (total hip and femoral neck but not lumbar spine) (116)

Signs to look out for include fatigue and lethargy, depression, irritability, headaches, difficulty with balance, decreased cognitive function, constipation, sore or swollen tongue, heart palpitations, mouth ulcers, pins and needles and changes to vision

10.1001/jama.295.10.1152