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The initial bursts reflect NO already released from GSNO during solution preparation and accumulated prior to injection

doi: 10.1016/j.cell.2018.05.003 74 Del PradoL.Jaraz-RodrguezM.AgroM.Zamora-DortaM.AzpiazuN.CallejaM.et al

The researchers said their results would justify other studies attempting to relate glutathione levels in the body with measures of brain dysfunction seen in disorders such as psychosis and schizophrenia

Too much signal and you waste money without additional benefit, the response curve plateaus rather than climbing indefinitely

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