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10.1097/00001813-199208000-00003 Anticancer Drugs 103 KavanaghJ

[DOI] [PubMed] [Google Scholar] 6.Jensen MD, Ryan DH, Apovian CM, Ard JD, Comuzzie AG, Donato KA, Hu FB, Hubbard VS, Jakicic JM, Kushner RF, Loria CM, Millen BE, Nonas CA, Pi-Sunyer FX, Stevens J, Stevens VJ, Wadden TA, Wolfe BM, Yanovski SZ G

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These data suggest that MYCN -amplified neuroblastoma cells with very high levels of MYCN are sensitive to a reduction of the intracellular cysteine pool by simultaneous inhibition of cystine import and cysteine synthesis via transsulfuration