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Acs, G., Palkovits, M

Erastin and sorafenib inhibit the expression of Nrf2 downstream target gene Xc - deplete GSH, induce ferroptosis, reduce cell viability, and enhance the sensitivity of NSCLC cells to cisplatin ( Ferroptosis may play a role in lung cancer radiotherapy

In vitro experiments assessed OSRs impact on OA chondrocyte proliferation, repair, and inflammation, focusing on Glutathione peroxidase 4 (GPX4) and solute carrier family 7 member 11 (SLC7A11) regulation

The future of autoimmune disease treatment will hinge on a personalized, multifaceted approach that incorporates immune modulation, tolerance establishment, and tissue regeneration

However, further exploration of other polyamine-catabolizing enzymes, such as SMOX and PAOX, could provide insights into polyamines and necroptosis