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Mension, E

Garro, S.R

Silibinin Silibinin A and silibinin B were reported to inhibit CYP2C9 in human liver microsomes using the clinically relevant probe (S)-warfarin at possibly therapeutic concentrations

A specific oxidoreductase, previously known as apoptosis-inducing-factor mitochondrial-2 (AIFM2), capable of recycling reduced ubiquinol (Co-enzymeQ 10 H 2 ) from ubiquinone at the expense of NAD(P)H, has been presented as a potential ferroptosis inhibitor due to the fact that its overexpression complements the loss of GPx4 in PFA1 and human fibrosarcoma (66, 67)

Fungal peroxisomes are specialized in both anabolism and catabolism with very important functions for cell protection by detoxifying and sequestering reactive oxygen species 49,50