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The pooled lentiviral supernatant was filtered through 0.45 m PVDF syringe filters (Whatman, 6746-2504), aliquoted and stored at 80 C

Acknowledgments This study was supported by Conselho Nacional de Desenvolvimento Cientfico e Tecnolgico (CNPq), Fundao de Amparo Pesquisa do estado de Minas Gerais (FAPEMIG/PRONEX), Coordenao de Aperfeioamento de Pessoal de Nvel Superior (CAPES)