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To test the Photostability upon laser irradiation, 200 L of PLGA nanoparticles encapsulating DDA-GSH-AuNCs, Nile red or fluorescein were placed in UV 96-Well microplate and irradiated with the following lasers: (364 nm, 80 mW, 248 mW/cm 2 ), (568 nm, 30 mW, 93 mW/cm 2 ) and (488 nm, 30 mW, 93 mW/cm 2 ), respectively using confocal laser scanning microscope (LSM 510 META, Carl Zeiss MicroImaging GmbH, Gttingen, Germany) for total duration of 20 minutes

Potentially severe side effects may result from prolonged CS use

Fades Dark Spots and Hyperpigmentation: It works at a cellular level to lighten acne scars , sun spots, and uneven pigmentation

The activity of the CS was measured using a Citrate Synthase (CS) Activity Assay Kit following the manufacturers instructions (Solarbio)

As well, as it can produce asthma or tinnitus