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Before considering this type of treatment, it is important to understand the current regulatory position in Singapore, what the available clinical evidence actually shows, and what evidence-based alternatives exist for managing skin concerns such as hyperpigmentation and uneven skin tone

The first and rate-limiting step, catalyzed by glutamate-cysteine ligase (GCL), generates -glutamylcysteine from glutamate and cysteine

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Certain types of GTs have antioxidant properties, such as dehydroascorbate reductase or glutathione peroxidases, and others are involved in hormone signaling (Noctor et al

Metabolomics 2010