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Treatment with ambroxol hydrochloride significantly increased glucosylceramidase activity in fibroblasts from healthy controls, Gaucher disease patients, and heterozygous glucocerebrosidase mutation carriers with PD

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Epidemiol Infect 143(14):31039 Costa DLC, Diniz JB, Requena G et al (2017) Randomized, double-blind, placebo-controlled trial of N-acetylcysteine augmentation for treatment-resistant obsessive-compulsive disorder

Representative domains include: Gastrointestinal and hepatic models: Protection against ulcers, leaky gut, IBSlike symptoms, Crohntype inflammation, and toxic liver injury (e.g., CCl4, NSAID, and alcohol models), with improved mucosal healing and barrier integrity