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Increased oxidative stress plays an important role in airway inflammation 12 and is often linked to enhanced ROS (reactive oxygen species) production or malfunction of antioxidant defenses 13,14

Given that cellular death plays a pivotal role in maintaining the homeostasis in our body, their importance is acknowledged across various research domains

This observation alludes to the heterogeneous nature of this disease that contributes to its complexity, thus making it difficult to completely understand its etiology